Balancing of Flow at Microfluidic Apertures

Computational fluid dynamic simulations were used to obtain a radially symmetrical flow profile at an aperture of microfluidic channel by manually arranging flow-directing obstacles around the aperture. For first time, was improved calculating coefficient variation (CoV), which applied velocity magnitude along coaxially arranged circles below in channel. A minimum CoV 0.03 obtained circle with same diameter as Channels optimized design fabricated lamination two layers dry film resist and patterned UV lithography. The formed using inductively coupled plasma reactive ion etching process. Video recording behavior confirmed simulation results experimentally. proposed oopimization method can favorably be for balanced hydrodynamic trapping particles or cells apertures. This article is protected copyright. All rights reserved.